What Is IGF-1 LR3? A Research Overview
A plain-language research overview of IGF-1 LR3 — what the long-acting IGF-1 analogue is, why it's studied, and how purity is verified. Research use only.

IGF-1 LR3 — Long R3 Insulin-like Growth Factor-1 — is a research analogue frequently used in cell-culture science. This overview covers what it is and what to check when sourcing it.
What IGF-1 LR3 Is
IGF-1 LR3 is an 83-amino-acid analogue of Insulin-like Growth Factor-1, engineered with an arginine substitution at position 3 and a 13-amino-acid N-terminal extension. These modifications extend its stability and reduce binding to IGF-binding proteins compared with native IGF-1.
Why Researchers Study It
IGF-1 LR3 is commonly used as a cell-culture supplement and in laboratory models of growth-factor signalling and cellular proliferation. All such work is in-vitro / preclinical.
How It Is Characterised in the Lab
Identity and quality are confirmed analytically rather than assumed. A credible research supply confirms identity by mass spectrometry (MS) and purity by HPLC — typically 99%+ — through an accredited (ISO 17025) third-party laboratory, with a per-batch Certificate of Analysis (COA) tied to the exact lot. The CAS reference is 946870-92-4.
Review the identity table, analytical data and per-batch documentation on the IGF-1 LR3 product page, or browse the full endocrine / GH research catalogue.
Research use only. IGF-1 LR3 research materials are supplied strictly for laboratory and analytical research and are not for human or animal consumption, diagnosis, treatment, or prevention of any disease.
Helio Peptides supplies research materials made in the USA, third-party tested to 99%+ purity, and shipped with a Certificate of Analysis. Browse research materials →