GHRP-6 - 5mg
About GHRP-6 - 5mg
GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic hexapeptide and one of the earliest growth hormone secretagogues to be characterized. Its sequence, His-D-Trp-Ala-Trp-D-Phe-Lys-NH2, contains D-configured tryptophan and phenylalanine residues that confer metabolic stability and receptor activity. It acts as an agonist at the growth hormone secretagogue receptor (GHS-R1a), the same receptor targeted by endogenous ghrelin, and stimulates GH release through a pathway distinct from GHRH.
As a foundational compound in secretagogue research, GHRP-6 is widely used as a reference agonist for characterizing ghrelin-receptor signaling and GH secretory responses. Unlike the more selective later-generation peptides, GHRP-6 is noted in the literature for also stimulating appetite and, at higher exposures, modestly influencing ACTH, cortisol and prolactin in model systems. Supplied as a lyophilized powder for research use only.
Research use only — not for human or animal consumption. Per-batch documentation is provided with the material.
Handling and Storage Tips:
Keep peptides cold and away from light once received.
For short-term use (days to weeks), refrigeration at 4°C (39°F) is acceptable.
Lyophilized peptides are typically stable at room temperature for several weeks, making it suitable for moderate-term storage.
For long-term storage (months to years), it’s best to freeze peptides at -80°C (-112°F). Freezing optimally preserves peptide stability for extended periods.
FDA Disclosure & Intended Use:
FDA Disclosure: The statements on this website and the products sold herein have not been evaluated by the U.S. Food and Drug Administration (FDA). These products are not intended to diagnose, treat, cure, or prevent any disease. Products sold are for Research Use Only and are not for human or animal use.
Intended Purpose: Products sold on this site are intended solely for basic laboratory research, pharmaceutical research, or the development of new tests. They are not intended for diagnostic, therapeutic, or clinical use.
Specifications
- MaterialGHRP-6 - 5mg
- Also searched asGHRP6, GHRP 6
- Research AreaGrowth Hormone Research
- Presentation—
- CAS Number87616-84-0
- Molecular FormulaC46H56N12O6
- Molecular Weight873.0 g/mol
- TypeSynthetic hexapeptide (growth hormone releasing peptide)
- Receptor / TargetGrowth hormone secretagogue receptor (GHS-R1a / ghrelin receptor)
- PubChem CID4345065 →
His-D-Trp-Ala-Trp-D-Phe-Lys-NH2
- Purity (HPLC)≥99%
- Identity (MS)Confirmed to specification
- TestingAccredited (ISO 17025) third-party laboratory
- DocumentationPer-batch COA →
GHRP-6 was among the first synthetic peptides shown to release GH through a receptor distinct from the GHRH receptor, work that ultimately contributed to the identification of the growth hormone secretagogue receptor and its endogenous ligand ghrelin. In model systems it produces robust GH secretion and characteristic GHS-R-mediated effects on appetite.
Because of its well-documented pharmacology and non-selective secretagogue profile, GHRP-6 remains a standard positive-control and reference compound in studies dissecting ghrelin-receptor signaling and comparing secretagogue selectivity across the GHRP family.
GHRP-6 was developed in the 1980s from the earlier enkephalin-derived GH-releasing peptides described by Bowers and colleagues, and became a key tool in the research that led to the discovery of the growth hormone secretagogue receptor in the 1990s and ghrelin in 1999. It remains a widely referenced early-generation growth hormone releasing peptide.
- Bowers CY, et al. On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone. Endocrinology. 1984;114(5):1537-1545.
- Howard AD, et al. A receptor in pituitary and hypothalamus that functions in growth hormone release. Science. 1996;273(5277):974-977.
- Kojima M, et al. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature. 1999;402(6762):656-660.
View compound profile on NIH PubChem →
Cited literature refers to laboratory and preclinical research. This material is supplied strictly for research use only and is not intended to diagnose, treat, cure, or prevent any disease.
Are these research materials third-party tested?
Yes — every batch is analysed by an accredited (ISO 17025) independent laboratory using HPLC and mass spectrometry, with a per-batch Certificate of Analysis.
What purity are the materials?
Materials are verified to 99%+ HPLC purity. Any batch that does not meet the threshold is not released.
Do you provide a Certificate of Analysis (COA)?
Yes. Per-batch COA documentation is provided and is traceable by lot number.
Where do you ship from?
Materials are shipped from the USA in discreet, protective packaging.
Are these products for human use?
No. All materials are sold strictly for laboratory research use only — not for human or animal consumption, diagnosis, treatment, or prevention of any disease.
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