Sermorelin 5MG Research Vial - GHRH Analogue | Third-Party Tested
About Sermorelin 5MG Research Vial - GHRH Analogue | Third-Party Tested
Sermorelin is a synthetic 29-amino-acid peptide corresponding to the biologically active N-terminal fragment of endogenous human growth hormone-releasing hormone, GHRH(1-29)-NH2. This fragment retains the full GH-releasing activity of the parent 44-residue hormone, making Sermorelin one of the most established GHRH-analog research tools for probing pulsatile growth-hormone secretion from the anterior pituitary.
In laboratory model systems, Sermorelin binds and activates the GHRH receptor, triggering cAMP-mediated signaling and GH release. Because it acts at the physiological GHRH receptor rather than the ghrelin receptor, it is frequently used as a reference GHRH agonist in studies comparing GHRH-axis and secretagogue pathways. Supplied as a lyophilized powder for research use only.
Research use only — not for human or animal consumption. Per-batch documentation is provided with the material.
Sermorelin 5MG Research Vial – GHRH Research Peptide | Third-Party Tested
Product Description
Sermorelin is a synthetic 29-amino-acid research peptide related to growth hormone-releasing hormone (GHRH). It is referenced in laboratory research examining GHRH receptor activity, peptide signaling, receptor interactions, and endocrine-system biochemical pathways.
Each Helio Peptides Sermorelin research vial contains 5MG of lyophilized research material.
Product Specifications
Compound: Sermorelin
Research Format: Lyophilized powder
Content: 5MG per vial
Batch produced and batch tested
Third-party analytical testing
Identity and purity verification
Certificate of Analysis available
Manufactured in the USA
Intended exclusively for laboratory research
Research Use Only
This product is intended solely for laboratory research purposes. Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease.
Specifications
- MaterialSermorelin 5MG Research Vial - GHRH Analogue | Third-Party Tested
- Research AreaGrowth Hormone Research
- Presentation—
- CAS Number86168-78-7
- Molecular FormulaC149H246N44O42S
- Molecular Weight3357.96 g/mol
- TypeSynthetic peptide (GHRH 1-29 analog)
- Receptor / TargetGrowth hormone-releasing hormone receptor (GHRH-R)
- PubChem CID16132413 →
Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
- Purity (HPLC)≥99%
- Identity (MS)Confirmed to specification
- TestingAccredited (ISO 17025) third-party laboratory
- DocumentationPer-batch COA →
Research on Sermorelin established that the GHRH(1-29) fragment is sufficient to reproduce the GH-releasing activity of full-length GHRH, providing a compact and synthetically tractable tool for GH-axis studies. In model systems it produces GHRH-receptor-mediated GH secretion with a short half-life, reflecting rapid enzymatic degradation of the unmodified sequence.
Comparative studies frequently use Sermorelin as the native-sequence reference against which DPP-IV-resistant and albumin-conjugated GHRH analogs are evaluated, highlighting how backbone modifications alter half-life and secretory pattern relative to the parent fragment.
Sermorelin (GHRH 1-29) was characterized in the 1980s following isolation and sequencing of human GHRH, and its acetate salt was later developed as a diagnostic and therapeutic GHRH agonist. It remains one of the most extensively studied GHRH-class peptides in the published literature and a standard reference tool in growth-hormone research.
- Guillemin R, et al. Growth hormone-releasing factor from a human pancreatic tumor that caused acromegaly. Science. 1982;218(4572):585-587.
- Rivier J, et al. Characterization of a growth hormone-releasing factor from a human pancreatic islet tumour. Nature. 1982;300(5889):276-278.
- Prakash A, Goa KL. Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency. BioDrugs. 1999;12(2):139-157.
View compound profile on NIH PubChem →
Cited literature refers to laboratory and preclinical research. This material is supplied strictly for research use only and is not intended to diagnose, treat, cure, or prevent any disease.
Are these research materials third-party tested?
Yes — every batch is analysed by an accredited (ISO 17025) independent laboratory using HPLC and mass spectrometry, with a per-batch Certificate of Analysis.
What purity are the materials?
Materials are verified to 99%+ HPLC purity. Any batch that does not meet the threshold is not released.
Do you provide a Certificate of Analysis (COA)?
Yes. Per-batch COA documentation is provided and is traceable by lot number.
Where do you ship from?
Materials are shipped from the USA in discreet, protective packaging.
Are these products for human use?
No. All materials are sold strictly for laboratory research use only — not for human or animal consumption, diagnosis, treatment, or prevention of any disease.
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