Skin & Cosmetic Research

Snap-8 10MG

CAS # 868844-74-0

A single-component research material supplied for controlled research environments. Suitable for studies involving mitochondrial-derived peptide characterization and method development in model systems.

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Purity≥99% HPLC
FormResearch material
CAS868844-74-0
TestingISO 17025 3rd-party
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About Snap-8 10MG

Snap-8, known by the INCI designation Acetyl Octapeptide-3, is an eight-amino-acid synthetic peptide (Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2) developed as a structurally extended analog of Acetyl Hexapeptide-8 (Argireline). It is catalogued under CAS 868844-74-0 and PubChem CID 76283482. The sequence corresponds to the N-terminal region of SNAP-25 and is studied as a competitive analog within SNARE-complex formation, the machinery underlying vesicular neurotransmitter release.

Helio's Snap-8 is manufactured by solid-phase peptide synthesis in a US-based facility, with identity confirmed by HPLC and mass spectrometry and third-party testing at an ISO 17025-accredited laboratory; a Certificate of Analysis is available on request. Supplied as a 10mg lyophilized vial, it is intended strictly for in vitro and preclinical Research Use Only and is not for human or veterinary use.

Research use only — not for human or animal consumption. Per-batch documentation is provided with the material.

Snap-8 (Acetyl Octapeptide-3) 10MG Research Vial | Third-Party Tested

Snap-8, also known as Acetyl Octapeptide-3, is a synthetic research peptide frequently referenced in cosmetic peptide, formulation, peptide-signaling, and laboratory skin-biology research.

Each Helio Peptides Snap-8 research vial contains 10MG of lyophilized research material.

Product Specifications

Compound: Snap-8 / Acetyl Octapeptide-3
Research Format: Lyophilized powder
Content: 10MG per vial
Batch produced and batch tested
Third-party analytical testing
Identity and purity verification
Certificate of Analysis available
Manufactured in the USA
Intended exclusively for laboratory research

Research Use Only

This product is intended solely for laboratory research purposes. Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease.

Specifications

Identification
  • MaterialSnap-8 10MG
  • Also searched asSnap8, Acetyl Octapeptide-3
  • Research AreaSkin & Cosmetic Research
  • Presentation
  • CAS Number868844-74-0
  • Molecular FormulaC41H70N16O16S
  • Molecular Weight1075.16 g/mol
  • TypeAcetylated, C-terminally amidated octapeptide
  • Receptor / TargetSNARE-complex / SNAP-25 competitive analog (neuromuscular signaling, in vitro)
  • PubChem CID76283482 →
Amino Acid Sequence

Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2 (Ac-EEMQRRAD-NH2)

Analytical Data
  • Purity (HPLC)≥99%
  • Identity (MS)Confirmed to specification
  • TestingAccredited (ISO 17025) third-party laboratory
  • DocumentationPer-batch COA →
Key Characteristics
Molecular FormulaC41H70N16O16S
Molecular Weight1075.16 g/mol
CAS Number868844-74-0
PubChem CID76283482
StructureAc-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2 (8 residues; acetylated N-terminus, amidated C-terminus)
Receptor / TargetSNARE / SNAP-25 competitive analog (in vitro)
FormLyophilized powder
SolubilityFreely soluble in water
StorageLyophilized: room temperature short-term; -20°C to -80°C long-term; protect from light
StabilityRefrigerate at 4°C for short-term use; freeze at -80°C for extended storage
Research Context
Neuromuscular signalingStudied as a SNAP-25-derived competitive analog within SNARE-complex assembly models.
Cosmetic peptide researchInvestigated in vitro for effects related to catecholamine and acetylcholine release.
Structure-activity studiesCompared with Acetyl Hexapeptide-8 (Argireline) as an extended-sequence analog.
Topical-formulation researchExamined for aqueous solubility and stability in cosmetic-formulation modeling.
Analytical method developmentWell-defined sequence used as an HPLC/MS reference peptide.
Research Findings

Snap-8 is studied as an extended analog of Acetyl Hexapeptide-8 that mimics the N-terminal domain of SNAP-25, a component of the SNARE complex governing vesicle-mediated neurotransmitter release. In vitro research explores whether competitive incorporation of the peptide can attenuate SNARE-complex formation, a mechanism of interest to cosmetic-peptide investigators.

Reported characterization emphasizes its high aqueous solubility and defined eight-residue structure. All work is in vitro or formulation-modeling in nature; no human efficacy or wrinkle-reduction claims are made here.

History

Snap-8 (Acetyl Octapeptide-3) was introduced in the cosmetic-peptide sector as a next-generation, sequence-extended successor to Acetyl Hexapeptide-8 (Argireline), designed to more closely mimic the SNAP-25 N-terminus for neuromuscular-signaling research.

References
  1. PubChem Compound Summary for CID 76283482, Acetyl Octapeptide-3. National Library of Medicine.
  2. Blanes-Mira C, et al. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310.
  3. BOC Sciences product record, SNAP-8 (CAS 868844-74-0).

View compound profile on NIH PubChem →

Cited literature refers to laboratory and preclinical research. This material is supplied strictly for research use only and is not intended to diagnose, treat, cure, or prevent any disease.

Why researchers choose Helio Peptides
99%+ PurityHPLC-verified every batch
Accredited TestingIndependent ISO 17025 laboratory
Per-Batch COADocumentation tied to your lot
Made in the USADiscreet, protected shipping
Frequently Asked
Are these research materials third-party tested?

Yes — every batch is analysed by an accredited (ISO 17025) independent laboratory using HPLC and mass spectrometry, with a per-batch Certificate of Analysis.

What purity are the materials?

Materials are verified to 99%+ HPLC purity. Any batch that does not meet the threshold is not released.

Do you provide a Certificate of Analysis (COA)?

Yes. Per-batch COA documentation is provided and is traceable by lot number.

Where do you ship from?

Materials are shipped from the USA in discreet, protective packaging.

Are these products for human use?

No. All materials are sold strictly for laboratory research use only — not for human or animal consumption, diagnosis, treatment, or prevention of any disease.

RESEARCH USE ONLY · NOT FOR HUMAN OR VETERINARY USE · 21+