Thymosin Alpha 1 5MG
About Thymosin Alpha 1 5MG
Thymosin Alpha-1 (TA-1, also called Tα1 or Thymalfasin) is a 28-amino-acid, N-terminally acetylated peptide originally isolated from the thymic tissue fraction Thymosin Fraction 5. Sequence-identical to the endogenous human peptide, it carries a molecular formula of C129H215N33O55 and a molecular weight of approximately 3,108 g/mol (CAS 62304-98-7). Its acetylated N-terminus is a defining structural feature confirmed by mass spectrometry.
TA-1 is one of the most extensively studied immunomodulatory peptides in the thymosin family. Research literature examines its interactions with Toll-like receptor signaling pathways, its influence on dendritic cell and T-cell maturation, and its modulation of cytokine networks and natural killer cell activity. Because it maps to endogenous thymic biology, it is widely used as a reference tool in immunology and infectious-disease models. Supplied for laboratory research use only.
Research use only — not for human or animal consumption. Per-batch documentation is provided with the material.
Thymosin Alpha 1 (TA-1) 5MG Research Vial | Third-Party Tested
Thymosin Alpha 1, commonly abbreviated TA-1, is a synthetic research peptide corresponding to a defined peptide sequence referenced in laboratory studies involving peptide signaling, cellular pathways, and immune-system biology.
Each Helio Peptides Thymosin Alpha 1 research vial contains 5MG of lyophilized research material.
Product Specifications
Compound: Thymosin Alpha 1 / TA-1
Research Format: Lyophilized powder
Content: 5MG per vial
Batch produced and batch tested
Third-party analytical testing
Identity and purity verification
Certificate of Analysis available
Manufactured in the USA
Intended exclusively for laboratory research
Research Use Only
This product is intended solely for laboratory research purposes. Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease.
Specifications
- MaterialThymosin Alpha 1 5MG
- Also searched asThymalfasin, Thymosin Alpha 1, TA-1
- Research AreaLongevity Research
- Presentation—
- CAS Number62304-98-7
- Molecular FormulaC129H215N33O55
- Molecular Weight3108.3 g/mol
- TypeAcetylated 28-residue peptide (thymic peptide fragment)
- Receptor / TargetToll-like receptors (notably TLR2 / TLR9) and innate/adaptive immune modulation
- PubChem CID16130571 →
Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH
- Purity (HPLC)≥99%
- Identity (MS)Confirmed to specification
- TestingAccredited (ISO 17025) third-party laboratory
- DocumentationPer-batch COA →
Research on Thymosin Alpha-1 describes pleiotropic immunomodulatory activity: enhancement of T-cell and dendritic cell maturation, augmentation of natural killer cell activity, and modulation of cytokine expression through Toll-like receptor signaling. It is one of the most clinically investigated thymic peptides internationally, with a substantial literature spanning viral infection, sepsis, and oncology models.
Reported effects derive from cell-culture systems, animal models, and clinical studies conducted outside the United States; findings are context-dependent and not established for U.S. therapeutic use. This material is offered strictly as a research reagent.
Thymosin Alpha-1 was first isolated and characterized in the 1970s by Allan Goldstein and colleagues from Thymosin Fraction 5, a thymic tissue extract. It was among the first thymic peptides to be fully sequenced and synthesized, and under the name thymalfasin it has been developed and studied internationally as an immunomodulator across infectious-disease and oncology contexts.
- Goldstein AL, et al. Thymosin alpha1: chemistry, mechanism of action, and applications. Ann N Y Acad Sci. 2007.
- Romani L, et al. Thymosin alpha1: an endogenous regulator of inflammation, immunity, and tolerance. Ann N Y Acad Sci. 2007;1112:326-338.
- King R, Tuthill C. Immune modulation with thymosin alpha 1 treatment. Vitam Horm. 2016;102:151-178.
- PubChem Compound Summary for CID 16130571, Thymalfasin. National Center for Biotechnology Information.
View compound profile on NIH PubChem →
Cited literature refers to laboratory and preclinical research. This material is supplied strictly for research use only and is not intended to diagnose, treat, cure, or prevent any disease.
Are these research materials third-party tested?
Yes — every batch is analysed by an accredited (ISO 17025) independent laboratory using HPLC and mass spectrometry, with a per-batch Certificate of Analysis.
What purity are the materials?
Materials are verified to 99%+ HPLC purity. Any batch that does not meet the threshold is not released.
Do you provide a Certificate of Analysis (COA)?
Yes. Per-batch COA documentation is provided and is traceable by lot number.
Where do you ship from?
Materials are shipped from the USA in discreet, protective packaging.
Are these products for human use?
No. All materials are sold strictly for laboratory research use only — not for human or animal consumption, diagnosis, treatment, or prevention of any disease.
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