Recovery Research

Bpc/Tb Liquid Spray

CAS # 137525-51-0 (BPC-157); 77591-33-4 (TB-500 / Thymosin Beta-4)

Helio Peptides – BP-C/TB Spray is a research-grade peptide formulation designed exclusively for scientific studies on recovery mechanisms, tissue repair, and related biological processes. Each spray delivers 300-350mcg of BPC-157 and TB-500 peptides, totaling 30 ml per bottle, ensuring precise dosing for controlled experimental use. Manufactured in the USA under strict quality control standards, this product is rigorously tested for purity and consistency to support reliable research outcomes.

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Purity≥99% HPLC
FormResearch material
CAS137525-51-0 (BPC-157); 77591-33-4 (TB-500 / Thymosin Beta-4)
TestingISO 17025 3rd-party
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About Bpc/Tb Liquid Spray

This product combines two of the most-studied recovery-research peptides, BPC-157 and TB-500 (Thymosin Beta-4), in a single lyophilized vial. BPC-157 is a synthetic pentadecapeptide (GEPPPGKPADDAGLV; C62H98N16O22; ~1419.5 g/mol; CAS 137525-51-0; PubChem CID 9941957) derived from a gastric-juice protein and studied for angiogenic and nitric-oxide-mediated tissue-repair mechanisms. TB-500 corresponds to full-length Thymosin Beta-4, a 43-residue N-acetylated peptide (C212H350N56O78S; ~4963 g/mol; CAS 77591-33-4; PubChem CID 16132341) that acts primarily by sequestering monomeric G-actin.

The two peptides are frequently paired in preclinical connective-tissue research because their proposed mechanisms are complementary: BPC-157 emphasizes vascular and nitric-oxide pathways, while TB-500 emphasizes actin-driven cell migration and cytoskeletal remodeling. Helio offers this blend in 5mg+5mg and 10mg+10mg vial configurations. This material is Research Use Only and is not for human or veterinary use.

Research use only — not for human or animal consumption. Per-batch documentation is provided with the material.

Handling and Storage Tips:

Keep peptides cold and away from light once received.

For short-term use (days to weeks), refrigeration at 4°C (39°F) is acceptable.

Lyophilized peptides are typically stable at room temperature for several weeks, making it suitable for moderate-term storage.

For long-term storage (months to years), it’s best to freeze peptides at -80°C (-112°F). Freezing optimally preserves peptide stability for extended periods.

FDA Disclosure & Intended Use:

FDA Disclosure: The statements on this website and the products sold herein have not been evaluated by the U.S. Food and Drug Administration (FDA). These products are not intended to diagnose, treat, cure, or prevent any disease. Products sold are for Research Use Only and are not for human or animal use.

Intended Purpose: Products sold on this site are intended solely for basic laboratory research, pharmaceutical research, or the development of new tests. They are not intended for diagnostic, therapeutic, or clinical use.

Specifications

Identification
  • MaterialBpc/Tb Liquid Spray
  • Research AreaRecovery Research
  • Presentation
  • CAS Number137525-51-0 (BPC-157); 77591-33-4 (TB-500 / Thymosin Beta-4)
  • Molecular FormulaC62H98N16O22 (BPC-157); C212H350N56O78S (TB-500)
  • Molecular Weight~1419.5 g/mol (BPC-157); ~4963.44 g/mol (TB-500)
  • TypeBlend of two synthetic peptides (pentadecapeptide + 43-residue Thymosin Beta-4)
  • Receptor / TargetBPC-157: VEGFR2 / NO-eNOS-Akt signaling (no defined receptor); TB-500: G-actin sequestration
Amino Acid Sequence

BPC-157: GEPPPGKPADDAGLV (15 aa); TB-500: Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES (43 aa)

Analytical Data
  • Purity (HPLC)≥99%
  • Identity (MS)Confirmed to specification
  • TestingAccredited (ISO 17025) third-party laboratory
  • DocumentationPer-batch COA →
Key Characteristics
Molecular FormulaC62H98N16O22 (BPC-157) + C212H350N56O78S (TB-500)
Molecular Weight~1419.5 g/mol (BPC-157); ~4963.44 g/mol (TB-500)
CAS Number137525-51-0 (BPC-157); 77591-33-4 (TB-500)
PubChem CID9941957 (BPC-157); 16132341 (TB-500)
StructureTwo linear synthetic peptides co-formulated (15 aa + 43 aa)
Receptor / TargetBPC-157: VEGFR2/NO-eNOS-Akt; TB-500: G-actin sequestration
FormLyophilized powder blend (vial)
SolubilityBoth peptides soluble in water and bacteriostatic water
StorageStore lyophilized at -20°C; reconstituted at 4°C short-term, -80°C long-term
StabilityStable as lyophilized powder; protect from light and minimize freeze-thaw in solution
Research Context
AngiogenesisBoth peptides are studied for pro-angiogenic effects, BPC-157 via VEGFR2 and TB-500 via its actin-binding motif.
Connective-tissue repairPaired in tendon, ligament and muscle injury research for complementary repair endpoints.
Cell migrationTB-500 promotes actin-driven migration of fibroblasts and endothelial cells.
Nitric oxide signalingBPC-157 contributes NO / eNOS-Akt-related cytoprotective effects.
Wound healingCombined use is explored in dermal and soft-tissue repair models.
Research Findings

The BPC-157 / TB-500 pairing is a common preclinical combination in recovery research because the two peptides target distinct but complementary processes, vascular and nitric-oxide signaling for BPC-157 and actin-cytoskeleton regulation and cell migration for TB-500. Individual-compound studies (Sikiric et al. for BPC-157; Malinda et al. and Goldstein et al. for Thymosin Beta-4) document angiogenic and tissue-repair endpoints in rodent and in-vitro models.

No controlled study establishes synergy or human efficacy of the blend itself; the two peptides are simply co-formulated for research convenience. All associated data are experimental and hypothesis-generating.

History

BPC-157 (from gastric-juice Body Protection Compound, 1990s) and Thymosin Beta-4 (isolated from thymus, characterized since the 1980s) each have independent experimental histories; their combination as a research blend reflects their shared use in connective-tissue and wound-repair studies. Both remain unapproved investigational compounds for laboratory research only.

References
  1. Seiwerth S, Brcic L, Vuletic LB, et al. BPC 157 and blood vessels. Current Pharmaceutical Design. 2014;20(7):1121-1125.
  2. Sikiric P, Seiwerth S, Rucman R, et al. Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract. Current Pharmaceutical Design. 2011;17(16):1612-1632.
  3. Malinda KM, Sidhu GS, Mani H, et al. Thymosin beta4 accelerates wound healing. Journal of Investigative Dermatology. 1999;113(3):364-368.
  4. Goldstein AL, Hannappel E, Kleinman HK. Thymosin beta4: actin-sequestering protein moonlights to repair injured tissues. Trends in Molecular Medicine. 2005;11(9):421-429.

Cited literature refers to laboratory and preclinical research. This material is supplied strictly for research use only and is not intended to diagnose, treat, cure, or prevent any disease.

Why researchers choose Helio Peptides
99%+ PurityHPLC-verified every batch
Accredited TestingIndependent ISO 17025 laboratory
Per-Batch COADocumentation tied to your lot
Made in the USADiscreet, protected shipping
Frequently Asked
Are these research materials third-party tested?

Yes — every batch is analysed by an accredited (ISO 17025) independent laboratory using HPLC and mass spectrometry, with a per-batch Certificate of Analysis.

What purity are the materials?

Materials are verified to 99%+ HPLC purity. Any batch that does not meet the threshold is not released.

Do you provide a Certificate of Analysis (COA)?

Yes. Per-batch COA documentation is provided and is traceable by lot number.

Where do you ship from?

Materials are shipped from the USA in discreet, protective packaging.

Are these products for human use?

No. All materials are sold strictly for laboratory research use only — not for human or animal consumption, diagnosis, treatment, or prevention of any disease.

RESEARCH USE ONLY · NOT FOR HUMAN OR VETERINARY USE · 21+